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Evidence Based Practice Clinical Guideline Review

Title of Guideline: PEP Topic: Chemotherapy Induced Nausea and Vomiting


  • Oncology Nursing Society Clinical Journal of Oncology Nursing
  • Janelle M. Tipton, MSN RN AOCN
  • Roxanne W. McDaniel, PhD RN
  • Laurel Barbour, RN MSN AOCN
  • Mary Pat Johnston, RN MS AOCN
  • Marilyn Kayne, BSN RN OCN
  • Patricia LeRoy, RN BSN OCN
  • Marita L. Ripple, RN OCN

Date of publication: 2007

Date of Review: August 2014

Method of Review: The Evidence Based Practice Protocol Review Subcommittee conducted a group review of the clinical guideline, followed by voting to arrive at a consensus recommendation. Because this protocol is from the Oncology Nursing Society, the subcommittee felt that a full review using the AGREE criteria1 was not necessary and an expedited review was conducted.

Review Summary: Although this protocol was written for adult oncology patients, the recommendations for CINV management can be adapted for the pediatric population. The protocol suggest some medications that are widely used in the pediatric population and would be appropriate with some dosing adjustments. The non-pharmacologic recommendations were appropriate for pediatric oncology patients.

Recommendation for use: Recommended with some modification for pediatric patients.

Access Guideline Return to Evidence Based Practice

1The AGREE Collaboration. Writing Group: Cluzeau FA, Burgers JS, Brouwers M, Grol R, Mäkelä M, Littlejohns P, Grimshaw J, Hunt C. Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project. Quality and Safety in Health Care 2003; 12(1): 18‐23. www. agreecollaboration.org