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Evidence Based Practice Clinical Guideline Review

PEP Topic: Chemotherapy Induced Nausea and Vomiting

Author(s) Jiyeon Lee, PhD RN ACNP-BC; Catherine Cherwin, PhD RN; Lynn M. Czaplewski, MS RN ACNS-BC CRNI AOCNS®; Rasha Dabbour, PhD; Myrna Doumit, PhD RN; Coleen Lewis, MSN ANP-BC AOCNP®; Deborah L. Selm-Orr, DNPMS RN CRNP AOCN®;  Kelli Thoele, MSN RN ACNS-BC BMTCN® OCN®; Susan Wesmiller, PhD RN and Stacy Whiteside, MS RN CPNP-AC/PC CPON®

Date of publication: April 2017| Date of Review: January 2018

Method of Review: The Evidence Based Practice Guideline Review Subcommittee conducted a review of the updated guideline using the Rapid Appraisal Checklist for Guidelines by Melnyk.1 Because this guideline was developed using a strict protocol by the Oncology Nursing Society, the subcommittee determined that an additional full review using the AGREE criteria was not necessary.

Review Summary: The guideline is based on the original adult-oriented guideline; however, development of the new Pediatric guideline is based exclusively on studies with subjects that were 18 years of age or younger. CINV management is still mainly drug-based, which imposes some limitations on the pediatric population. The guideline includes some medications considered safe for the pediatric population, with dosing adjustments. Non-pharmacologic interventions are still limited and understudied in this population.

Recommendation for use: Appropriate for APHON Members

Access Guideline Return to Evidence Based Practice

1Melnyk, B.M. & Fineout-Overholt, E. (2011). Appendix D: Rapid Critical Appraisal Checklist for Evidence Based Clinical Practice Guidelines. In Evidence-Based practice in nursing & healthcare. (2nded.). (p. 518). Philadelphia, PA: Lippincott, Williams & Wilkins.