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Evidence Based Practice 

APHON's Evidence Based Practice and Research Committee supports the development of Evidence-Based Practice Guidelines and supports research activities within the membership optimizing outcomes for children, adolescents and young adults with cancer and blood disorders.

Clinical Guidelines

The APHON Evidence Based Practice and Research Committee has reviewed these guidelines and recommends them as appropriate for APHON members:

American Brain Tumor Association/American Association of Neuroscience Nurses

Date of Publication: 2014 | Date of Review: June 2014

Care of the Pediatric Patient with a Brain Tumor AANN Clinical Practice Guideline Series

Children's Oncology Group

Date of Publication: 2018 | Date of Review: July 30, 2018

Assessment Tools for Peripheral Neuropathy in Pediatric Oncology: A Systematic Review from the Children’s Oncology Group

Journal of Clinical Oncology

Date of Publication: 2012 | Date of Review: October 2014

Guideline for the Management of Fever and Neutropenia in Children With Cancer and/or Undergoing Hematopoietic Stem-Cell Transplantation

Journal of Pediatric Oncology Nursing

Date of Publication: 2014 | Date of Review: March 4, 2018

Evidence Based Practice Recommendations for Hydration in Children and Adolescents with Cancer Receiving Intravenous Cyclophosphamide

Date of Publication: 2014 | Date of Review: May 10, 2018

Evidence Based Practice Recommendations to Prevent/Manage Post Lumbar Puncture Headaches in Pediatric Patients Receiving Intrathecal Chemotherapy

Date of Publication: 2014 | Date of Review: April 2, 2018

Evidence Based Practice Recommendations to Fertility Preservation Options for Inclusion in Treatment Protocols for Pediatric and Adolescent Patients Diagnosed with Cancer

The National Consensus Project for Quality Palliative Care

Date of Publication: 2013 | Date of Review: December 17, 2013

Clinical Practice Guidelines for Quality Palliative Care, 3rd edition

National Comprehensive Cancer Network®

Date of Publication: April 2014 | Date of Review: August 2014

NCCN Clinical Practice Guidelines in Oncology Adolescent and Young Adult (AYA) Oncology

National Heart, Lung, and Blood Institute

Date of Publication: September 2014 | Date of Review: December 2017

Evidence-Based Management of Sickle Cell Disease: Expert Panel Report

Oncology Nursing Society (ONS)

Date of Publication: 2008 | Date of Review: 

PEP Topic: Mucositis

Date of Publication: 2007 | Date of Review:

PEP Topic: Chemotherapy Induced Nausea and Vomiting

Date of Publication: 2006 | Date of Review:

PEP Topic: Prevention of Infection

Pediatric Oncology Group of Ontario (POGO)

Date of Publication: April 23, 2014 | Date of Review: June 2014

Guideline for the Prevention and Treatment of Anticipatory Nausea and Vomiting due to Chemotherapy in Pediatric Cancer Patients

Date of Publication: February 28, 2013 | Date of Review: June 2014

Guideline for the Prevention of Acute Nausea and Vomiting due to Antineoplastic Medication in Pediatric Cancer Patients

World Health Organization (WHO)

Date of Publication: 2014 | Date of Review: October 2014

WHO Guidelines on the Pharmacological Treatment of Persisting Pain in Children with Medical Illnesses

Resources for developing an Evidenced Based Practice Project

Duke University EBP tutorial | American Nursing Association EBP Toolkit | University of Maryland Evidenced Based Practice Site

Research Tools

The Cochrane Database | US National Library/ National Institutes of Health | National Guideline Clearinghouse | Turning Research into Practice

Additional Resource