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Aplastic Anemia Webinar Archive

Aplastic Anemia: Fill 'Er Up! But With What?

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Acquired aplastic anemia is a rare but potentially fatal bone marrow failure syndrome. Transplant with a matched sibling donor is the treatment of choice for severe aplastic anemia. But what should be offered to the majority of children and young adults who do not have this option? Is immunosuppressive therapy with ATG and cyclosporine safer and more effective than high dose cyclophosphamide? When should transplant with an alternative stem cell source be considered? And what new agents are being studied in children with newly diagnosed and refractory disease? Through several case studies we'll review best practice guidelines for managing children and adolescents with aplastic anemia including treatment selection, supportive care guidelines, and monitoring for complications of both the disease and therapies.


Karyn J. Brundige, MSN CPNP ARNP 
Dana-Farber and Boston Children's
Cancer and Blood Disorders Center
Bone Marrow Failure and MDS Program
Boston, MA


  1. Contrast front line therapies (transplant vs medical therapy) for severe aplastic anemia. 

  2. Review supportive care guidelines for aplastic anemia.

  3. Discuss second line therapies for refractory or relapsed disease.

Accreditation and Disclaimers

Individual Learning Needs Assessment (ILNA) Coding

The program content has been reviewed by the Oncology Nursing Certification Corporation (ONCC) and is acceptable for recertification points.

CPHON® Blueprint

Disease Related Biology or Treatment

BMTCN® Blueprint

Types of Transplant and Source of Stem Cells or Preparative Regimens and Stem Cell Infusion

ONCC review is only for designating content to be used for recertification points and is not for CNE accreditation. CNE programs must be formally approved for contact hours by an acceptable accreditor/approver of nursing CE to be used for recertification by ONCC. If the CNE provider fails to obtain formal approval to award contact hours by an acceptable accrediting/approval body, no information related to ONCC recertification may be used in relation to the program. Have questions regarding the CPHON® ILNA Coding? Please visit the ONCC website or call them toll-free at 877.769.ONCC (US and Canada only).

Accreditation Statement

The Association of Pediatric Hematology/Oncology Nurses (APHON) is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.


A staff member, volunteer (faculty), or their family member who has an affiliation with a commercial company must declare that relationship in advance of involvement with an education activity that could be used as a forum to promote the interest of that company and its products. The material presented in this activity represents the opinion of the presenters and not necessarily the views of APHON.

There are no disclosures to report for this activity.

Off-Label Use

No off-label use was discussed.

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