Clinical Guideline Review
Guideline for the Management of Fever and Neutropenia in Children with Cancer and/or Undergoing Hematopoietic Stem Cell Transplantation (Long Version)
Author(s): Thomas Lehrnbecher; Robert Phillips; Sarah Alexander; Frank Alvaro; Fabianne Carlesse; Brian Fisher; Hana Hakim; Maria Santolaya; Elio Castagnola; Bonnie L. Davis; L. Lee Dupuis; Faith Gibson; Andreas H. Groll; Aditya Gaur; Ajay Gupta; Rejin Kebudi; Sérgio Petrilli; William J. Steinbach; Milena Villarroel; Theo Zaoutis; and Lillian Sung
Date of publication: 2012 | Date of Review: June 2014
Method of Review: The Evidence Based Practice Protocol Review Subcommittee conducted a group review of the clinical guideline. As this protocol has been endorsed by the Children’s Oncology Group, and expedited review was done without using the AGREE guidelines1. The committee read through the guideline and a consensus was reached regarding the recommendation for endorsement.
Review Summary: This is well written, well referenced guideline that makes research- based sound recommendations for clinical management. Although written for use for patients in Canada, the recommendations can be safely translated to practice for patient in the United States.
Recommendation for use: Recommended for use in pediatric oncology.
1The AGREE Collaboration. Writing Group: Cluzeau FA, Burgers JS, Brouwers M, Grol R, Mäkelä M, Littlejohns P, Grimshaw J, Hunt C. Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project. Quality and Safety in Health Care 2003; 12(1): 18‐23. www. agreecollaboration.org