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Foundations of Pediatric Hematopoietic Stem Cell Transplantation: 3rd Edition Now Available

The primary resource designed explicitly to educate new pediatric hematology/oncology nurses on caring for pediatric transplant patients is now available! The Transplant Foundations course is designed to teach nurse learners how to care for pediatric transplant patients at their institution. The new edition of the course provides both a self-paced independent learning experience and classroom instruction. This course emphasizes the following:

  • Core foundational concepts that are required before learning specific institutional practices
  • A multi-disciplinary team approach and plan of care
  • Providing psychosocial support and education for patients, parents, and family members about what to do/expect during their care.

This course is meant to be paired with classroom training about institutional-specific pediatric transplant practices. Providing these online modules reduces the nurse educator's preparation time and time in the classroom. The new edition of the course provides both a self-paced independent learning experience and classroom instruction. Each module is available in PowerPoint format with presenter notes allowing nurse educators' to use the content in the classroom setting. 

Target Audience

This course is written for the following target audiences.

  • Novice nurses with limited pediatric clinical experience and no stem cell transplant experience.
  • Experienced nurses who don't have hematology, oncology, bone marrow transplant (BMT), or pediatric experience. These nurses may know about adult stem cell transplants but have not cared for pediatric patients.
  • Nurse Practitioners who may have some experience but not extensive transplant experience.

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Learn About the Course Objectives

After completing the Transplant Foundations course, the nurse will be able to:

  • Identify and define the types and sources of transplants
  • Identify indications for transplants and ethical considerations
  • Identify the types of conditioning regimens for BMT and their potential adverse effects
  • Administer and manage cellular therapy infusions
  • Conduct assessments specific to pediatric BMT patients
  • Manage symptoms as needed and required (pain, mucositis, nausea, vomiting, skin integrity, etc.)
  • Recognize the complications for each type of transplant regardless of donor source or conditioning regimen
    • In the event of an emergency, immediately intervene
    • For non-emergencies, notify/escalate to the appropriate provider, who should intervene
  • Describe post-transplantation immune re-constitution and late effects after BMT
  • Plan for safe discharge, including home and follow-up care
  • Maintain professional boundaries and care for self
  • Care for an initial, small cohort, less complicated stem cell patient.
Learn About the Course Modules

Module 1

Module Instructor: Rita Secola, PhD RN CPON® NEABC FAAN
By the end of this module, participants will be able to:

  1. describe the goals of hematopoietic stem cell transplantation (HSCT)
  2. describe the types of HSCT and indications for its use
  3. explain the ethical considerations related to HSCT.

Module 2

Module Instructor: Rita Secola, PhD RN CPON® NEABC FAAN

By the end of this module, participants will be able to:

  1. describe HSCT donor types and selections
  2. define HSCT stem cell sources and collections
  3. describe other HSCT cellular therapy.

Module 3

Module Instructor: Rita Secola, PhD RN CPON® NEABC FAAN

By the end of this module, participants will be able to:

  1. describe the principles of HSCT conditioning regimens
  2. define types of HSCT conditioning regimens
  3. explain patient care and monitoring related to HSCT conditioning regimens.

Module 4

Module Instructor: Karen Wolownik, MSN RN CPNP CPHON®

By the end of this module, participants will be able to:

  1. define the different types of stem cell infusions and the implication for the use of each
  2. identify methods of stem cell product manipulation and explain the procs and cons of using each
  3. understand implications and ABO incompatibility
  4. describe the preparation of the patient and environment and the necessary monitoring for cell therapy infusions
  5. identify expected minor and serious adverse events of stem cell infusion and nursing management
  6. describe psychosocial considerations in caring for patients undergoing cell therapy infusions.

Module 5

Module Instructor: Misty Evans, DNP APRN CPNP-AC BMTCN®

By the end of this module, participants will be able to:

  1. recognize common toxicities following HSCT
  2. identify nursing interventions to prevent and manage toxicities following HSCT.

Module 6

Module Instructor: Karen Wolownik, MSN RN CPNP CPHON®

By the end of this module, participants will be able to:

  1. describe the pathophysiology of acute and chronic Graft-Versus-Host Disease (GVHD)
  2. recognize the signs and symptoms of acute and chronic GVHD
  3. describe and demonstrate an understanding of the staging and grading guidelines for GVHD
  4. describe the most common prophylactic and management strategies for acute and chronic GVHD.

Module 7

Module Instructor: Misty Evans, DNP APRN CPNP-AC BMTCN®

By the end of this module, participants will be able to:

  1. determine appropriate discharge criteria following HSCT
  2. identify patient, and caregiver education needs following HSCT
  3. explain ongoing follow-up of the post-transplant patient after the hospital discharge.

Module 8

Module Instructor: Misty Evans, DNP APRN CPNP-AC BMTCN®

By the end of this module, participants will be able to:

  1. describe the late complications of HSCT
  2. recognize the risk factors associated with late complications of HSCT
  3. identify diagnostic tests to monitor long-term complications of HSCT
  4. describe the recommended survivorship follow-up for HSCT survivors.

Module 9

Module Instructor: Janice Nuuhiwa, MSN RN NPD-BC CPHON®

By the end of this module, participants will be able to:

  1. identify expectations for maintaining professional boundaries when caring for chronic, long-term patients receiving HSCT
  2. describe a relationship-based model of care's essential components
  3. define provider well-being within the context of personal and team accountability.

Meet the Course Content Developers

Photo of author Misty Evans

Misty Evans, DNP APRN CPNP-AC BMTCN®

Nurse Practitioner, Assistant Professor

Vanderbilt University

Nashville, Tennessee

Image of author Janice Nuuhiwa

Janice Nuuhiwa, MSN RN NPD-BC CPHON®

Nursing Professional Development Specialist

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois

Photo of author Rita Secola

Rita L. Secola, PhD RN NEA-BC CPON® FAAN

Clinical Service Director

Children's Hospital Los Angeles

Los Angeles, California

Photo of author Karen Wolownik

Karen Wolownik, MSN RN CPNP CPHON®

Pediatric Nurse Practitioner, Clinical Educator

Maria Fareri Children's Hospital NY Medical College

Valhalla, New York

Course Reviewers

Caroline Costello, MBA BSN RN CPON® BMTCN® NPD-BC

Nursing Education Coordinator

Boston Children's Hospital

Boston, Massachusetts

Ellen Olson, MS RN CPNP CPHON® BMTCN®

Blood and Marrow Transplant Nurse Practitioner

Children's Healthcare of Atlanta/Aflac Cancer Center & Blood Disorders

Atlanta, Georgia

CNE Contact Hours

Participants that complete the online self-paced version of the course will earn 9 CNE contact hours. All modules have an end-of-module quiz with feedback for correct and incorrect answers. Successful completion of the module quizzes will be required to move forward in the course.

To complete the course and earn CNE contact hours, self-paced participants must pass all module quizzes. Each individual must complete the self-paced version of the course to earn CNE contact hours. CNE contact hours are not provided by APHON for courses taught by nurse educators within the hospital setting.

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