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Hemophagocytic Lymphohistiocytosis (HLH) Across Pediatric Specialties: Spotlight on Immune Effector Cell HLH Like Syndrome
March 13 @ 9:00 am – 6:30 pm America/New York
We invite you as we convene experts from Duke Cancer Institute and major academic societies including Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network-HCT Cancer Immunotherapy Subgroup, American Society of Transplant and Cellular Therapy (ASTCT), European Blood and Marrow Transplant (EBMT) Group and ICU Oncology Kids in Europe Research Group (POKER).
About the conference: Cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS), are well-recognized toxicities associated with immune effector cell therapies, and in particular, chimeric antigen receptor (CAR) T cell therapy. There is increasing recognition that hemophagocytic lymphohistiocytosis (HLH)-like toxicities following CAR T cell infusion are occurring broadly across patient populations and CAR T cell constructs. At this symposia, we convene experts across pediatric and adult specialties to discuss and guide future research, advocacy and clinical priorities related to IEC-HLH Like Syndrome.
At the conference, we will:
explore other hyper-inflammatory disorders as it may inform future IEC-HLH Like Syndrome management strategies
discuss our current understanding of HLH, hyper-inflammatory and HLH Like Syndromes
review current state and future landscape for immune effector cell therapies
discuss recent ASTCT criteria for diagnosis and management IEC-HLH Like Syndrome criteria
To learn more, go to: Hemophagocytic Lymphohistiocytosis (HLH) Across Pediatric Specialties: Spotlight on Immune Effector Cell HLH Like Syndrome | Duke Department of Pediatrics