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Renewal Program

2022chemobiorenewal2To ensure that Pediatric Chemotherapy/Biotherapy Providers stay current in their knowledge of safe chemotherapy and biotherapy administration, APHON requires active Providers to renew their status. 

The first renewal will occur within two years of attending a pediatric chemotherapy/biotherapy provider course and achieving a passing score on the post-test and will then occur every three years after that. This is an essential part of the Pediatric Chemotherapy/Biotherapy Provider Program, which allows all Providers to keep pace with the ever-changing advancement in medicine and technology.

This online program asks participants to read updated administration material, take a post-test, and complete an evaluation. Upon successful completion, participants will be awarded two continuing nursing education (CNE) contact hours.

Content of the Program

  • Drug Shortages
  • Fertility Preservation
  • Neurotoxicities of Chemotherapy and Biotherapy
  • Small Molecule Inhibitors

The renewal exam consists of 25 questions, and you must achieve a minimum score of 80% to pass. If you are unsuccessful in your first attempt, you will be permitted to retake the exam one time at no additional cost. If you do not achieve a passing score after two attempts, you will be required to retake the 2-day provider course.

Learning Outcome

As a result of participating in this educational activity, the learner will gain specific knowledge, according to national standards, that is needed to safely and consistently administer chemotherapy and biotherapy to children and adolescents. Post-testing and evaluations will evidence the measurement of this outcome.

Renewal Dates

The dates for provider renewals are as follows (please refer to your provider card for the issue date):

Provider Card Issue Date

Renewal Deadlines

1/1/2020-12/31/2020 12/31/2022
1/1/2021-12/31/2021 12/31/2023
1/1/2022-12/31/2022 12/31/2024

Renewal Fee Structure

US & High Income Countries


Member: $65
Nonmember: $85


Member: $85
Nonmember: $105

International Pricing

Pediatric Hematology/Oncology Nurses from middle-low income countries receive a discount on the Pediatric Chemotherapy/Biotherapy Provider renewal fee. Low-income economies are defined as those with a GNI per capita, calculated using the World Bank Atlas method, of $1,005 or less. Middle-income economies are those with a GNI per capita between $1,006 and $3955. Upper middle-income economies have a GNI per capita between $3,956 and $12,235, and high-income economies are those with a GNI per capita of $12,236 or more.

View the Tier 1: Low-Income Economy Countries (80% Discount)

October Rate: $13 for Members | $17 for non-members

November/December Rate: $17 for members | $21 for nonmembers

Afghanistan | Burkina Faso | Burundi | Central African Republic | Chad | Congo, Dem. Rep. | Eritrea| Ethiopia | Gambia, The | Guinea | Guinea-Bissau | Korea, Dem. People's Rep. | Liberia | Madagascar | Malawi | Mali | Mozambique | Niger | Rwanda | Sierra Leone | Somalia | Sudan | Togo | Uganda |Yemen, Rep.

View the Tier 2: Low-Middle Income Economy Countries (70% Discount)

October Rate:  $19.50 for Members | $25.50 for non-members

November/December Rate: $25.50 for members | $31.50 for nonmembers

Angola | Benin | Bangladesh | Bhutan | Bolivia | Cabo Verde | Cambodia | Cameroon | Comoros | Congo, Rep. | Côte d'Ivoire | Djibouti | Egypt, Arab Rep. | Eswatini | Ghana | Haiti | Honduras | India | Kenya | Kiribati | Kyrgyz Republic | Lao PDR | Lesotho | Mauritania | Micronesia, Fed. Sts. | Mongolia | Morocco | Myanmar | Nepal | Nicaragua | Nigeria | Pakistan | Papua New Guinea | Philippines | São Tomé and Principe | Senegal | Solomon Islands | South Sudan | Syrian Arab Republic | Tajikistan | Tanzania | Timor-Leste | Tunisia | Ukraine | Uzbekistan | Vanuatu | Vietnam | Yemen, Rep. | Zambia | Zimbabwe

View Tier 3: Upper-Middle Income Economy Countries (60% Discount)

October Rate: $26 for Members | $34 for non-members

November/December Rate: $34 for members | $42 for nonmembers

Albania | Algeria | American Samoa | Argentina | Armenia | Azerbaijan | Belarus Belize | Bosnia and Herzegovina | Botswana | Brazil | Bulgaria | China | Colombia | Costa Rica | Cuba | Dominica | Dominican Republic | Ecuador | El Salvador | Equatorial Guinea | Fiji | Gabon | Georgia | Grenada | Guatemala | Guyana | Indonesia | Iran, Islamic Rep. | Iraq | Jamaica | Jordan | Kazakhstan | Kosovo | Lebanon | Libya | Macedonia, FYR | Malaysia | Maldives| Marshall Islands | Mexico | Moldova | Montenegro | Namibia | Paraguay | Peru | Russian Federation | Samoa | Serbia | South Africa | Sri Lanka | St. Lucia | St. Vincent and the Grenadines | Suriname | Thailand | Tonga | Turkey | Turkmenistan | Tuvalu | West Bank and Gaza | Panama


Provider Renewal


Current Pediatric Chemotherapy/Biotherapy providers that expire on December 31, 2022, may now renew their provider status. The renewal is open October 1-December 31, 2022.

To renew your Pediatric Chemotherapy/Biotherapy provider status, log into your APHON website account and select the option to pay the open balance on your account for the 2022 English Chemotherapy/Biotherapy Provider Renewal Exam. You may reset your password online if you have forgotten your login information or contact member services by phone at 855.202.9760 (US Residents Only) 847.375.4724 or by This email address is being protected from spambots. You need JavaScript enabled to view it. for assistance.

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Accessing the Renewal System

Once payment has been submitted, log in to your APHON website account and select My Library. Click on the hat icon next to the 2022 English (or Spanish) Chemotherapy/Biotherapy Provider Renewal Exam to get started. You may log into the renewal system and view the downloadable PDF renewal content as often as you like until you are ready to take the exam. Please note that the exam must be completed by December 31, 2022, to maintain your Pediatric Chemotherapy/Biotherapy Provider status.

The renewal fee may be submitted online using a valid credit card by clicking the "Process My Order" button. Submitting payment will take a few seconds; please click the submit order button one time to avoid being charged more than once. 

Alternatively, you may download your renewal invoice and mail a check payment to our office. Please note that mailing a check payment will delay your access to the renewal exam. Your access to the renewal exam will be active once the payment has been processed. Please note that the renewal exam must be completed by December 31, 2022, to maintain your Pediatric Chemotherapy/Biotherapy Provider status. Extensions will not be granted beyond this date due to payment arrival by mail.

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Provider Renewal Policies

How do I pay for the renewal?

You may log into your APHON website account and select the option to pay your open balance. Click the check box adjacent to your order number to add the renewal to your shopping cart, and then enter your payment information to submit your payment online with a credit card.

If you wish to mail in a check payment, you may click the link on your Chemo/Bio Provider Renewal order number and select the option for a "Printable View." All checks should be mailed to our office at PO Box 3781, Oak Brook, IL 60522. Please allow 3 weeks for check payments to be received and processed. Check payments must be received in our office by December 31 to receive the early pricing. Also, the payment must be received in our office, applied to your account, and you MUST complete the renewal exam by December 31, 2022, to maintain your chemotherapy/biotherapy provider status.

How are Pediatric Chemotherapy/Biotherapy providers notified that they are due to renew their status?

APHON will attempt to contact providers who are due to complete their renewal by postcard and multiple email communications before the end of the year. However, it is the responsibility of the provider to provide APHON with updated contact information, know their expiration date, and renew on time. Providers can locate their expiration date by downloading their provider card from their My Library page, looking up their name in the online Provider Directory, or calling APHON Member Services at 855.202.9760 (US Residents Only) 847.375.4724, or by This email address is being protected from spambots. You need JavaScript enabled to view it. for assistance.

When are pediatric Chemotherapy/Biotherapy providers eligible to renew their status?

Current Pediatric Chemotherapy/Biotherapy providers that expire on December 31, 2022, may renew their provider status starting on October 1. The 2022 renewal cycle is from October 1 through December 31, 2022.

Can I re-take the 2-day Chemotherapy/Biotherapy Provider Course to renew or extend my provider status?

Chemotherapy/Biotherapy providers may take the course again if they feel that they need to revisit the concepts taught. However, providers must participate in the online renewal process to maintain their chemotherapy/biotherapy provider status. Taking a Chemotherapy/Biotherapy Provider course multiple times will not extend the renewal date for current providers.

How much time do I have to complete the Pediatric Chemotherapy/Biotherapy renewal exam once I start?

You can log in and out of the system as many times as you'd like to read the downloadable renewal packet PDF until December 31, 2021 (11 pm CST). Log into the exam to begin the 90-minute timer and complete the 25-question open book exam when you are ready. Should you run out of time, the exam will tabulate your score as it stands at the end of the 90 minutes. You must achieve a minimum score of 80% to pass. You will be allowed to retake the post-test one additional time if you fail the first attempt at no additional fee. If you fail both attempts, you will be required to retake the 2-day provider course.

When is the deadline to complete the pediatric chemotherapy/biotherapy renewal exam?

The exam must be completed by 11:59 pm Central Time on December 31, 2022.

Note: Staff support will not be available to assist with technical issues on weekend days. We strongly encourage all providers to initiate the renewal process during normal business hours when staff can provide support.

You will not be permitted to take the exam after 11:59 pm Central Time, December 31, 2022, regardless of whether a payment was submitted, nor will a refund be given. Additionally, no refunds will be given for failure to complete the exam by December 31, 2022, or failure to achieve a passing score on the exam.

If I renew during this renewal period, when will my next expiration be?

You will be given an issue date of 01/01/2023 and an expiration date of 12/31/2025. Your new renewal window will open on October 1, 2025, for you.

Is this an open exam book?

Yes, you may refer to your Pediatric Chemotherapy/Biotherapy Provider Program Curriculum textbook. There will also be an updated PDF document featuring updated administration material you need to read before taking the renewal. The questions on the exam will come from the updated downloadable PDF.

If I should fail my first attempt, do I get a second chance?

Yes, you will be allowed to retake the post-test one additional time if you fail the first attempt at no additional fee.

I purchased the exam and logged in to read the updated materials. Do I need to complete the exam right away, or can I log out and log back in later?

You can log in and out of the system as many times as you'd like until December 31, 2022 (11:59 pm CST). The 90-minute exam timer does not begin until you log into the exam.

How do Pediatric Chemotherapy/Biotherapy Providers that previously completed the exam access their continuing nursing education certificate?

Providers that previously completed the renewal process may access their CNE certificate by logging into their APHON website account. Users will be required to log in using their APHON website ID and password.

What is the refund/cancellation policy?

All orders are final once payment is submitted. APHON reserves the right to refuse to refund duplicate payments submitted for the provider renewal exam. We strongly encourage providers to verify previous payment submissions before completing the renewal exam purchase.

Accreditation and Disclaimer

Pharmacology Content

This program may also be recognized for 1.2 hours of pharmacology content indicated as calculated by the APHON Pediatric Chemotherapy/Biotherapy Provider Program Committee. APHON does not award pharmacology credit. APHON recommends that attendees retain a copy of the certificate for supportive documentation to submit to your state's nursing board. Please note that you may not apply CNE toward pharmacology content. The content may be used in only one area, nursing contact hours, or pharmacology content.

Official ONCC Statement and Disclaimer

The program content has been reviewed by the Oncology Nursing Certification Corporation (ONCC) and is acceptable for recertification points in the following areas: 

Basic Concepts for Transplantation, Care Continuum, Care of the Pediatric Hematology and Oncology Patient, Coordination of Care, Diagnosis and Staging, Disease-Related Biology, Early Post-transplant Management, End-of-Life, Foundations of Transplant, Graft-versus-Host Disease Prevention Management, Health Promotion/Screening, and Early Detection, 0.00 Late Post-Traumatic Management, Oncology Nursing Practice, Quality of Life, Palliative Care, Pre-Transplant Care, Preparative Regimens, Professional Practice, Psychosocial, Roles of the APN, Scientific Basis for Practice, Survivorship, Symptom Management, Treatment, Types of Transplants and Sources of Stem Cells, 0.00 Oncologic Emergencies.

Disclaimer: ONCC review is only for designating content to be used for recertification points and is not for CNE accreditation. CNE programs must be formally approved for contact hours by an acceptable accreditor/approver of nursing CE to be used for recertification by ONCC. If the CNE provider fails to obtain formal approval to award contact hours by an acceptable accrediting/approval body, no information related to ONCC recertification may be used in relation to the program.

Course content applies to multiple content areas across multiple credentials. Individual nurses' learning plans are linked to the ONCC Test Blueprint for the certification they hold. Review the current test blueprint available on the ONCC website to determine where the content fits.

Accreditation Statement

Association of Pediatric Hematology/Oncology Nurses (APHON) is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Centers' Commission on Accreditation.


A staff member, volunteer, or family member who has an affiliation with a commercial company must declare that relationship in advance of involvement with an educational activity that could be used as a forum to promote the interest of that company and its products. There are no disclosures to report for this activity.