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Evidence Based Practice Clinical Guideline Review

Evidence Based Practice Recommendations to Fertility Preservation Options for Inclusion in Treatment Protocols for Pediatric and Adolescent Patients Diagnosed with Cancer

Author(s): Alison Fernbach, MSN RN CPNP; Barbara Lockart, MSN RN CPNP CPON®; Cheryl L. Armus, MSN RN FNP; Lisa Bashore, PhD RN CPNP CPON®; Jennifer Levine, MD MSW; Leah Kroon, MN RN; Genevieve Sylvain, RN CPHON®; and Cheryl Rodgers, PhD RN CPNP CPON®

Date of Publication: 2014 | Date of Review: April 2, 2018

Citation: Journal of Pediatric Oncology Nursing, 2014, Vol 31 (4). pp. 211-222

Method of Review: A subcommittee of the Evidence Based Practice and Research Committee of the Association of Pediatric Hematology/Oncology Nurses conducted a group review of the clinical recommendations using the AGREE II criteria1. The committee had an overall assessment of approval for endorsement.

Review Summary: Fertility preservation issues are of utmost importance in pediatric oncology. This article clearly outlines the fertility preservation recommendations for Pediatric and AYA patients with cancer. It reviews the different options for both female and male patients. It also clearly rates the quality of the evidence that supports the recommendation. This is an area of patient care that is rapidly evolving and there may be even more updated evidence and options for FP available now.

Recommendation for use: Strongly recommend for endorsement

Disclaimer: These are not Evidence Based Practice (EBP) guidelines but are a systematic review of literature with EBP recommendations. Not all components of the AGEE II review instrument are met. The instrument is designed specifically for guideline review. The AGREE II instrument does allow for an objective assessment of quality. The EBP/Nursing Research Committee agrees that the value of these pediatric oncology EBP recommendations merit their posting on the APHON website.


1AGREE Next Steps Consortium (2009). The AGREE II Instrument [Electronic version]. Retrieved May, 2018, from www.agreetrust.org.

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